Study on strengthening terminal disinfection to reduce the nosocomial infection of multi-drug resistant organisms in intensive care unit
Objective To evaluate the effect of intensive terminal disinfection on nosocomial infection of multi-drug resistant orgamisms(MDRO).Methods The data from 2017 to 2019 were retrospectively investigated as the pre-intervention group,and the data from 2020 to 2021 were prospectively monitored as the post-intervention group.The discovery rate,bacteria composition ratio,and detection rate of MDRO nosocomial infection before and after intervention were compared.Results On the basis of routine disinfection in a primary intensive care unit(ICU)medical area,vaporized hydrogen peroxide technology was used to strengthen the terminal disinfection.The discovery rate of MDRO nosocomial infection after intervention was 1.84％,which was lower than 2.83％before intervention(P＜0.05).After the intervention,the constituent ratio of multidrug-resistant Acinetobacter baumannii(MDRAB)and carbapenem-resistant Serratia marcescens(CRSM)and the detection rate of nosocomial infection decreased(P＜0.05).The detection rate of nosocomial infection caused by carbapenem-resistant Klebsiella pneumoniae(CRKP)did not increase statistically,but the constituent ratio increased(P＜0.05).Conclusion Intensive terminal disinfection can reduce nosocomial infections caused by MDRO,but we need to pay attention to nosocomial infections caused by carbapenem-resistant Enterobacteriaceae(CRE),especially CRKP.
intensive care unitintensive terminal disinfectionMDROnosocomial infection
万方数据
维普
