首页|3类季铵盐的持续抗菌效果比较

3类季铵盐的持续抗菌效果比较

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目的 研究3类单链季铵盐对白念珠菌的持续抗菌效果,为筛选抗菌产品提供理论支持.方法 采用载体持续抗菌试验方法,对溴型、氯型和碳酸型3类季铵盐持续抗菌效果进行比较观察.结果 溴型、氯型和碳酸型季铵盐均用活性物浓度为2 000 mg/L,对载体上白念珠菌的持续抗菌时限分别达到95、95和59 d,在抗菌有效期限内仍可保持细菌减少率≥90%.溴型和氯型季铵盐抗菌效果持续时间明显长于碳酸型季铵盐.结论 3类季铵盐均具有较好的持续抗菌作用,溴型和氯型季铵盐的持续抗菌效果更长.
Comparison of sustained antibacterial effect of three kinds of quaternary ammonium salts
Objective To study the sustained antibacterial effects of three single chain quaternary ammonium salts against Candida albicans and to provide theoretical support for screening antibacterial products.Methods The carrier sustained antibacterial test method was used to compare and observe the sustained antibacterial effects of three kinds of quaternary ammonium salts:bromine,chlorine,and carbonate.Results Bromine,chlorine,and carbonate quaternary ammonium salts were all used with an active substance concentration of 2 000 mg/L,and their sustained antibacterial time against Candida albicans on the carrier reached 95,95,and 59 d,respectively.Within the antibacterial validity period,the bacterial reduction rate was still maintained at ≥ 90%.The antibacterial effect of bromine and chlorine quaternary ammonium salts lasted longer than that of carbonate quaternary ammonium salts significantly.Conclusion All three kinds of quaternary ammonium salts have good sustained antibacterial effects,with bromine and chlorine quaternary ammonium salts having longer sustained antibacterial effects.

sustained antibacterial effectquaternary ammonium saltCandida albicans

李艳红、唐小雪、张亮亮、张现兰、葛海哲

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山东利尔康医疗科技股份有限公司,山东德州 253032

持续抗菌效果 季铵盐 白念珠菌

2024

中国消毒学杂志
军事医学科学院疾病预防控制所,中华预防医学会

中国消毒学杂志

CSTPCD
影响因子:0.754
ISSN:1001-7658
年,卷(期):2024.41(6)
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