Comparison of sustained antibacterial effect of three kinds of quaternary ammonium salts
Objective To study the sustained antibacterial effects of three single chain quaternary ammonium salts against Candida albicans and to provide theoretical support for screening antibacterial products.Methods The carrier sustained antibacterial test method was used to compare and observe the sustained antibacterial effects of three kinds of quaternary ammonium salts:bromine,chlorine,and carbonate.Results Bromine,chlorine,and carbonate quaternary ammonium salts were all used with an active substance concentration of 2 000 mg/L,and their sustained antibacterial time against Candida albicans on the carrier reached 95,95,and 59 d,respectively.Within the antibacterial validity period,the bacterial reduction rate was still maintained at ≥ 90%.The antibacterial effect of bromine and chlorine quaternary ammonium salts lasted longer than that of carbonate quaternary ammonium salts significantly.Conclusion All three kinds of quaternary ammonium salts have good sustained antibacterial effects,with bromine and chlorine quaternary ammonium salts having longer sustained antibacterial effects.