Disinfection performance of a free hand-quick-drying hand sanitizer
Objective To test the disinfection-related performance and toxicity of hydrogen peroxide-ethanol free hand-drying hand sanitizer.Methods Quantitative suspension killing test,physical and chemical test,animal toxicity test methods were used to test the killing performance and safety of the disinfectant.Results The hand sanitizer has hydrogen peroxide and ethanol as the main composite germicidal components,with hydrogen peroxide content of 1 470 mg/L and ethanol content of 80.1％by volume.After 0.5,1.0 and 1.5 min of the hydrogen peroxide-ethanol hand sanitizer,the killing log value of Staphylococcus aureus,Escherichia coli and Pseudomonas aeruginosa were all>6.00,and the average killing log value of Candida albicans was>5.00,and the average killing log value of the poliovirus-Ⅰ vaccine strain was>4.00.The hand disinfectant liquid was used for hand wipe disinfection,and the killing log value of natural bacteria on the hand after 1 min was>1.00.The disinfectant sealed package was stored at 37℃for 3 months,and the reduction rates of its effective ingredient content were all less than 10％.The skin irritation test results of this hand sanitizer showed that it was non-irritating.The results of the acute oral toxicity test showed that the hand sanitizer was practically non-toxic to mice.The result of micronucleus test for mouse bone marrow polychromatic redblood cells was negative.Conclusion This hydrogen peroxide-ethanol hand sanitizer has a rapid killing effect on bacterial propagules,fungi and viruses.It is practically non-toxic and has stable storage properties.
hand sanitizerbacteriafungusvirusdisinfection effect
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