Disinfection effect and related performance of a compound quaternary ammonium salt disinfectant at low temperature
Objective To study the disinfection effect,corrosive effect on metals and toxicity to experimental animals of a certain compound quaternary ammonium disinfectant with ethylene glycol as antifreeze at low temperature.Methods Under the condition of-18℃,the disinfection effect of 500 mg/L compound quaternary ammonium salt disinfectant was evaluated with incubating the test bacteria for 3,6 and 9 min,respectively.The corrosion rates of stainless steel,carbon steel,copper and aluminum were evaluated,and the safety toxicology of disinfectants was evaluated by acute oral toxicity test,skin irritation test and acute eye irritation test.Results At-18℃,the killing log values of 500 mg/L disinfectant against Escherichia coli and Staphylococcus aureus on the carrier were 3.46 and>6.04,respectively.Corrosion rates(mm/a)of stainless steel,carbon steel,copper and aluminum by 500 mg/L disinfectant were 0.003 5,0.013 8,0.015 2 and 0.007 5 mm/a,respectively.The acute oral LD50 of 5 times concentration of the disinfectant was>5 000 mg/(kg·bw)in both male and female mice.It was non-irritating in a complete skin irritation test and acute eye irritation test in rabbits.Conclusion The compound quaternary ammonium salt disinfectant has a strong bactericidal effect at low temperature.It is basically non-corrosive to stainless steel and aluminum,and has good safety.
quaternary ammonium salt disinfectantbacterial propagulesdisinfection effecttoxicity
NETL
NSTL
万方数据
