Distribution and drug resistance of pathogens in sputum culture of pediatric inpatients
Objective To analyze the distribution and drug resistance of pathogenic bacteria in sputum cultures of pediatric inpatients in a hospital from 2017 to 2021.Methods The pathogenic bacteria culture and drug sensitivity results of sputum samples of pediatric inpatients in the hospital were retrospectively analyzed.Duplicate samples of the same patient were excluded.Drug sensitivity test and result judgment were accorded with CLSI standard.Results A total of 738 pathogenic bacteria were detected in 10 889 sputum samples,and the detection rate was 6.78%.Among them,G+bacteria was of 74.39%.G-bacteria was of 24.93%and fungi was of 0.68%.G+bacteria were mainly Streptococcus pneumoniae and Staphylococcus aureus.G-bacteria were mainly Escherichia coli.The resistance rates of Streptococcus pneumoniae to erythromycin and clindamycin were 97.87%and 96.05%,respectively.The resistance rates of Staphylococcus aureus to penicillin,erythromycin and ampicillin were 77.99%,61.01%and 57.23%respectively.The resistance rates of Escherichia coli to compound sulfamethoxazole and ampicillin were 52.13%and 41.49%respectively.Conclusion G+bacteria are the main pathogens cultured in sputum samples.Antibiotics should be used reasonably.