Pathogen distribution and drug resistance of nosocomial infection after orthopedic surgery
Objective To understand the occurrence of nosocomial infection,the distribution of pathogenic bacteria and the drug resistance after orthopedic surgery,so as to provide the basis for diagnosis and treatment of nosocomial infection and scientific selection of antibiotics.Methods Patients who underwent orthopedic surgery in hospital from January 2019 to December 2021 were selected as the study objects.The basic information of patients was collected,and the occurrence of postoperative nosocomial infection,pathogenic bacteria distribution and drug resistance were statistically analyzed.Results The overall incidence of nosocomial infection after orthopedic surgery was 0.34%,and the most common infection sites were lower respiratory tract,urinary tract and surgical site.The proportion of nosocomial infected patients after orthopedic surgery was highest in hip,followed by spine and lower limb.The most detected pathogens were Escherichia coli(24.82%),Staphylococcus epidermidis(11.68%),Staphylococcus aureus(10.95%),Klebsiellapneumoniae(7.30%),Enterobacter cloacae(5.84%),Staphylococcus haemolyticus(3.65%)and Acinetobacterbaumannii(3.65%).Surgical site infections were most common with gram-positive bacteria,while lower respiratory tract infections and urinary tract infections were most common with gram-negative bacteria.Staphylococcus was sensitive to tetracycline,levofloxacin,linezolid and vancomycin.The main gram-negative bacteria were highly sensitive to amikacin,piperacillin/tazobactam and carbapenems.Conclusion Pathogenic bacteria of postoperative orthopedic infection are widely distributed and the drug resistance is complex and diverse.It is necessary to strengthen specimen submission and select antibiotics rationally according to the results of drug resistance detection.
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