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某三甲医院多重耐药菌医院感染目标性监测分析

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目的 了解某三甲医院临床分离的多重耐药菌(MDRO)及其医院感染分布特点,为有效防控提供支持.方法 通过回顾性调查方法,对 2018-2022 年该医院住院患者MDRO感染情况及特点进行监测与分析.结果 连续 5 年共检出病原菌 14 597 株,其中MDRO 2 819 株,检出率为 19.31%.MDRO以耐碳青霉烯类菌株为主,耐碳青霉烯鲍曼不动杆菌(CR-AB)、耐甲氧西林金黄色葡萄球菌(MRSA)、耐碳青霉烯铜绿假单胞菌(CR-PA)、耐碳青霉烯类肺炎克雷伯菌(CR-KPN)和耐碳青霉烯肠杆菌(CRE)的检出率依次为 54.46%、37.86%、35.84%、25.17%和12.84%.MDRO医院感染部位主要为下呼吸道、血液和泌尿道,分别占 51.15%、12.79%和 12.46%.感染主要发生在ICU、普外科和血液科,分别占 40.33%、13.44%和 11.48%.结论 该医院MDRO检出率较高,但感染率处于下降趋势,应加强MDRO医院感染高发科室、高发部位的监测和防控管理.
Target monitoring and analysis on nosocomial infection of multi-drug resistant organisms in a grade 3A hospital
Objective To observe the distribution of multi-drug resistant organisms(MDRO)in a grade 3A hospital,so as to provide data for prevention policies and measures.Methods Retrospective survey was conducted to monitor and analyze the MDRO infection status and characteristics of hospitalized patients in the hospital from 2018 to 2022.Results A totel of 14 597 strains of pathogenic bacteria were detected in 5 years,among which 2 819 strains of MDRO were isolated,with the detection rate of 19.31%.MDRO was mainly composed of carbapenem resistant strains,and the detection rate of carbapenem resistant Acinetobacter baumannii(CR-AB),methicillin-resistant Staphylococcus aureus(MRSA),carbapenem resistant Pseudomonas aeruginosa(CR-PA),carbapenem resistant Klebsiella pneumoniae(CR-KPN),and carbapenem resistant Enterobacterium(CRE)was 54.46%,37.86%,35.84%,25.17%,and 12.84%,respectively.The main infection sites caused by MDRO were lower respiratory tract,blood,and urinary tract,accounting for 51.15%,12.79%,and 12.46%,respectively.Infection mainly occured in ICU,general surgery,and hematology,accounting for 40.33%,13.44%,and 11.48%,respectively.Conclusions The MDRO detection rate in this hospital is relatively high,however,the infection rate shows a downward trend.It is necessary to strengthen the monitoring and prevention and control management of high-risk departments and high-risk sites of MDRO hospital infection.

pathogenmulti-drug resistant organismsnosocomial infectionmonitoring

吕林芳、张汉阳、李从欣

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首都医科大学附属北京友谊医院,北京 100050

北京市疾病预防控制中心

河北医科大学第三医院

病原菌 多重耐药菌 医院感染 监测

国家自然科学基金

82003878

2024

中国消毒学杂志
军事医学科学院疾病预防控制所,中华预防医学会

中国消毒学杂志

CSTPCD
影响因子:0.754
ISSN:1001-7658
年,卷(期):2024.41(9)