Study on the effect of erythrosine-mediated photodynamic inactivation on influenza A viruses
Objective To investigate the effect of erythrosine-mediated photodynamic inactivation(PDI)on influenza A virus.Methods Cell culture method was used to observe the effect of erythrosine-mediated PDI on influenza A H1N1,H3N2,and H9N2 viruses.Results 50 μmol/L erythrosine was illuminated with blue LED light for 5 min,and the average inactivation logarithmic values of influenza A H1N1,H3N2,and H9N2 were 5.44,2.56,and 4.89 TCID50,respectively.The inactivation rates of erythrosine-mediated PDI on influenza A H1N1,H3N2,and H9N2 viruses on surfaces of different materials were≥99.99%,≥99.72%,and≥99.97%,respectively.Conclusion The erythrosine-mediated PDI has a good inactivation effect on influenza A H1N1,H3N2,and H9N2 viruses.
erythrosinephotodynamic inactivationinfluenza A virusinactivation effect