Characteristics and drug resistance analysis of Salmonella typhimurium infection in children
Objective To understand the characteristics and drug resistance of Salmonella typhimurium infection in children.Methods Through retrospective analysis and drug sensitivity testing,the clinical data and drug sensitivity test results of hospitalized children with Salmonella typhimurium infection in pediatric department of a hospital were statistically analyzed.Results Among the 105 pediatric patients with Salmonella typhimurium infection included in the analysis,there were 30 cases,24 cases,26 cases,10 cases and 15 cases respectively from 2017 to 2021,showing a decreasing trend year by year.The affected population was mainly children under 3 years old,with 96 cases,accounting for 91.43%of the total number of cases.The Salmonella typhimurium detected in the submitted samples from pediatric patients was sensitive to imipenem and ertapenem,with low resistance rates to levofloxacin,ceftriaxone,piperacillin/tazobactam,and amoxicillin/clavulanate potassium.It had a high resistance rate to compound sulfamethoxazole,amikacin,cefuroxime,etc.Conclusion Children infected with Salmonella typhimurium in Lishui district are mostly infants and young children aged 0 to 3 years old.Clinically isolated strains are sensitive to most commonly used antibiotics,and antibiotics can be selected based on drug sensitivity tests.
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