Study on the Inhibitory Activities of Hinokitiol and Its Combinations Against Malassezia
The inhibitory properties of hinokitiol and its combinations on Malassezia were investigated.The MIC of hinokitiol on Malassezia furfurwas 3.91 μg/mL.Fe2+could inactivate hinokitiol,while EDTA disodium enhanced the activity of hinokitiol.γ-undecalactone,γ-nonalactone,and thioctic acid played a synergistic,additive,and irrelevant role combined with hinokitiol against M.furfur,respectively.The combination containing hinokitiol,EDTA disodium,γ-undecalactone,γ-nonolactone and thioctic acid had excellent inhibitory ability against M.furfur,M.globosa,M.sloffii,M.sympodialis and M.obtusa.This study provides a solid basis for the application of hinokitiol and its combinations in the field of Malassezia inhibition.
万方数据
维普
