Effects of Moisturizers Containing Camellia Extract and Ganoderma Extract on Human Skin Micro-Ecology
To investigate the impact of natural plant extracts from Camellia japonica and Ganoderma lucidum on human skin micro-ecology,aiming to provide a theoretical foundation for the development and application of natural plant-based skincare products.Two moisturizers containing extracts derived from Camellia japonica and Ganoderma lucidum were employed in this study as the auxiliary materials.By using 16S rRNA and ITS rRNA high-throughput sequencing technology,in conjunction with capacitance-based determination of skin cuticle moisture content,we revealed the changes in diversity and population structure of skin microbial communities prior to moisturizers application,as well as at 14-day and 28-day intervals post-application.The utilization of moisturizers resulted in an increased diversity of bacterial communities,while simultaneously reducing the fungal species count.The samples from the D0,D14,and D28 groups exhibited distinct clustering patterns with evident discrimination.However,at the phylum level,there were no alterations observed in the community composition of skin microorganisms following the application of these two moisturizers.Firmicutes,Bacteroidetes,Proteobacteria,and Actinobacteria remained as dominant bacteria both before and after using the moisturizers;likewise Ascomycetes and Basidiomycetes persisted as dominant fungi.At the genus level,Staphylococcus and Epidermotrichum showed a significant increase in relative abundance among bacteria upon utilizing of moisturizers;however,changes in relative abundance among fungal genera appeared disordered.Furthermore,employing these two moisturizers greatly enhanced moisture content within the stratum corneum.The two moisturizers containing extracts from Camellia and Ganoderma possess the capability to effectively hydrate and replenish the skin,while also regulating and enhancing the micro-ecological balance of cutaneous flora.
Moisturizersskinmicro-ecologyhigh-throughput sequencing techniquewater content of stratum corneum
万方数据
维普
