Significance and Approach of Increasing Drug Loading in Solid Preparation of Traditional Chinese Medicine
Drug loading is an important index to evaluate the quality of solid preparation of traditional Chinese medicine.Drug loading is restricted by drug characteristics,dosage form,process,and drug delivery in vivo,which affects the preparation process,therapeutic effect,and drug release rate.By consulting domestic and foreign literature,this paper put forward the significance of increasing the drug loading:improving the compliance of patients,reducing the production cost,reducing the risk of the excipients.In this review,the possible approaches to increase drug loading,such as the selection of high-efficiency excipients,suitable drug preparation techniques,and modification of the physical properties of drugs are summarized.It will provide theoretical basis through this review for the development of high drug loading and high-quality formulations.
drug loadingdrug carriertraditional Chinese medicine preparationscompliance of patientsunification of medicines and excipients
万方数据
维普
