Transient receptor potential vanilloid-1(TRPV1)channel is a non-selective ligand-gated cationic channel with multiple activation mechanisms in the transient receptor potential subfamily.In recent years,a large number of studies have found that TRPV1 plays an important role in the field of cardiovascular diseases such as hypertension and atherosclerosis.With the in-depth study of traditional Chinese medicine,it has been found that Chinese medicine monomers and their active components can activate or inhibit TRPV1 channels,which has certain potential in the study of cardiovascular diseases.In this paper,the role of TRPV1 channel in cardiovascular diseases and the research progress of traditional Chinese medicine prevention and treatment of cardiovascular diseases based on TRPV1 channel are reviewed,in order to provide new ideas for prevention and treatment of cardiovascular system diseases.
关键词
瞬时受体电位香草素亚型1/辣椒素受体/心血管疾病/中医药
Key words
transient receptor potential vanilloid-1/capsaicin receptor/cardiovascular diseases/traditional chinese medicine
维普
万方数据