中国现代应用药学2024,Vol.41Issue(9) :1255-1258.DOI:10.13748/j.cnki.issn1007-7693.20232558

临床药师参与1例儿童药物超敏反应综合征的药学监护实践

Pharmaceutical Care Practice for A Case of Drug-induced Hypersensitivity Syndrome in A Child by Clinical Pharmacists

张询研 杨强 唐平秀 张鹏
中国现代应用药学2024,Vol.41Issue(9) :1255-1258.DOI:10.13748/j.cnki.issn1007-7693.20232558

临床药师参与1例儿童药物超敏反应综合征的药学监护实践

Pharmaceutical Care Practice for A Case of Drug-induced Hypersensitivity Syndrome in A Child by Clinical Pharmacists

张询研 1杨强 1唐平秀 1张鹏1
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作者信息

  • 1. 遂宁市中心医院,四川遂宁 629000
  • 折叠

摘要

目的 探讨万古霉素致药物超敏反应综合征的药学监护要点.方法 临床药师对1例万古霉素致药物超敏反应综合征儿童实施药学监护,调整患儿用药方案,监测抗菌药物血药浓度并调整给药剂量,并进行相关文献分析.结果 经过早期识别并停用可疑致敏药物后,患儿经对症支持治疗后病情好转出院.结论 儿童药物超敏反应综合征患者具有儿童的特殊性,临床医师与临床药师应重点关注特殊人群的用药安全,做到早发现、早治疗.

Abstract

OBJECTIVE To explore the key points of pharmaceutical care of drug-induced hypersensitivity syndrome caused by vancomycin.METHODS The clinical pharmacists performed pharmaceutical care for a case of vancomycin-induced drug hypersensitivity syndrome in a child,adjusted the child's medication regimens,monitored antimicrobial blood concentrations and adjusted the administered dose,and performed a relevant literature analysis.RESULTS After early identification and discontinuation of the suspected sensitizing drugs,the child was discharged from the hospital after symptomatic supportive treatment.CONCLUSION Children with drug-induced hypersensitivity syndrome have the special characteristics of children,clinicians and clinical pharmacists should focus on the medication safety of the special group to achieve early detection and early treatment.

关键词

临床药师/儿童/万古霉素/药物超敏反应综合征

Key words

clinical pharmacist/children/vancomycin/drug-induced hypersensitivity syndrome

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出版年

2024
中国现代应用药学
中国药学会

中国现代应用药学

CSTPCDCSCD北大核心
影响因子:0.877
ISSN:1007-7693
参考文献量15
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