首页|毒性中药饮片在门诊老年患者中的临床应用回顾性分析

毒性中药饮片在门诊老年患者中的临床应用回顾性分析

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目的 分析毒性中药饮片在绍兴市中医院门诊老年患者中的临床应用情况,探讨其用药的临床特点。方法 收集整理2022年6月-2023年6月绍兴市中医院门诊老年患者含毒性中药饮片处方数据,对患者性别、年龄、临床诊断、使用频数、超剂量情况等进行回顾性统计分析。结果 获得毒性中药饮片处方共12946张,涉及41味毒性中药,含毒性中药饮片条目数17474条。据患者年龄组与性别分布统计,60~69岁老年患者使用毒性中药饮片情况最多,女性患者略多于男性患者。据疾病分布统计,毒性中药饮片处方临床诊断多集中在痹证类病、咳嗽病、腰痛病、积聚病和伤筋病等。据使用情况统计,使用频数前5位的毒性中药饮片分别为苦杏仁、艾叶、川楝子、蜈蚣和制川乌。有22味毒性中药饮片存在不同程度的超剂量使用情况,其中超剂量使用占比前3位的中药为蛇六谷、雷公藤、山豆根,平均超剂量使用程度前3位的中药为制草乌、蛇六谷、制川乌。单张处方大多使用1味毒性中药饮片,毒性中药饮片联用≥2味的共7 897条。结论 毒性中药饮片在笔者所在医院老年患者中应用比较广泛,总体用药情况符合临床疾病需求,但需警惕毒性中药超剂量使用和毒性中药联用可能造成的不良反应。
Retrospective Analysis of the Clinical Application of Toxic Traditional Chinese Medicine Decoction Pieces in Elderly Outpatient Patients
OBJECTIVE To analyze the use and distribution characteristics of toxic traditional Chinese medicine(TCM)pieces in elderly outpatient patients in Shaoxing Hospital of Traditional Chinese Medicine,and to explore the clinical characteristics of their medication.METHODS The prescription data of elderly patients with toxic TCM decoction pieces in the outpatient department of Shaoxing Hospital of Traditional Chinese Medicine from June 2022 to June 2023 were collected,and analyzed retrospectively on the gender,age,clinical diagnosis,frequency and overdosage of use.RESULTS Among the 12 946 outpatient prescriptions of TCM decoction pieces for elderly patients,41 toxic TCM were involved with 17 474 prescriptions.According to the statistics of age group and gender distribution of patients,the elderly patients aged 60-69 years used the most toxic Chinese medicine slices,and the female patients were slightly more than the male patients.According to the statistics of disease distribution,the application of toxic TCM decoction pieces in elderly patients was mainly concentrated in Bi-syndrome diseases,cough disease,lumbago disease,accumulation disease and tendon disease.According to the statistics of use,the top 5 toxic TCM decoction pieces used frequently were fried Armenicacae Semen Amarum,Artemisiae Argyi Folium,Toosendan Fructus,Scolopendra,and Aconiti Radix Cocta.There were 22 toxic Chinese herbal slices with different degrees of overdose use,among which the top 3 Chinese herbs with the proportion of overdose use were Amorphophalli Rhizoma,Tripterygii Radix,and Sophorae Tonkinensis Radix and Rhizoma,and the top 3 Chinese herbs with the degree of overdose use were Aconiti Radix Cocta,Amorphophalli Rhizoma,and Aconiti Kusnezoffii Radix Cocta.In a single prescription,more than one piece of toxic traditional Chinese medicine was used and 7 897 pieces of 2 or more toxic traditional Chinese medicine decoction pieces were used in combination.CONCLUSION Toxic TCM decoction pieces are widely used in elderly patients in anthor's hospital,and it is reasonable.However,it is necessary to be aware of the potential risks of overdose and combined use of toxic TCM.

toxic traditional Chinese medicine decoction pieceselderly patientsoutpatientretrospective analysis

朱文瑞、赵亚萍、徐洪锋

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绍兴市中医院,中药剂科,浙江绍兴 312000

绍兴市中医院,西药剂科,浙江绍兴 312000

绍兴市中医院,临床药学室,浙江绍兴 312000

毒性中药饮片 老年患者 门诊 回顾性分析

国家中医药管理局沈元良全国名老中医药专家传承工作室建设项目浙江省中医药科技项目浙江省中医药科技项目浙江省中医药科技项目浙江省药学会医院药学专项科研资助项目

国中医药办人教函[2022]75号2023ZL7282023ZF1742023ZL7292019ZYY09

2024

中国现代应用药学
中国药学会

中国现代应用药学

CSTPCD北大核心
影响因子:0.877
ISSN:1007-7693
年,卷(期):2024.41(15)