Nine muskmelon varieties cultivated in Hainan were used as experimental materials to determine the mineral el-ement content in four parts(peel,flesh,core,and seed)of the fruits at mature period using inductively coupled plasma mass spectrometry(ICP-MS).The results showed that there were significant differences in the mineral element content in different parts of the fruits.Among the 17 elements,K,Mg,P,Na,Fe,and Zn had higher content,while Cu,Mn,Al,Co,Ni,B,Se,Rb,Sr,and Ba had lower content.Among the four parts,Mn,Ba,Al,Ca,and Sr elements had higher content in the peel and seed than that in the flesh and core,while Co,Cu,Zn,Se,B,Rb,K,and Mg elements had higher content in the seed than that in the other three parts.The peel of muskmelon contained higher levels of K,Mg,Na,P,Ca,Fe,Zn,Al,and B than that of thin-skinned muskmelons.The core of smooth-skinned muskmelons exhibited higher concentration of K,Mg,Na,Fe,Cu,Mn,Co,and B than that of thin-skinned muskmelons.The seed of thin-skinned melons had higher P,Zn,and B concentration than that of muskmelon and smooth-skinned melons.The peel and seed of muskmelon fruits con-tained higher mineral element content,and muskmelon exhibited a higher nutritional value in terms of mineral elements compared to smooth-skinned and thin-skinned muskmelons.The results provide new insights for the high-efficiency agri-cultural development of muskmelons in Hainan and serve as a reference for the comprehensive development and utiliza-tion of muskmelons.