Study on the correlation between the location of adenomyosis and the outcome of in vitro fertilization-embryo transfer
Objective To investigate the effect of lesion location on the outcome of in vitro fertilization-embryo transfer(IVF-ET)in patients with adenomyosis.Methods A total of 335 patients with adenomyosis who were admitted to Tangshan Maternal and Child Health Hospital from October 2019 to October 2022 with pregnancy intention were selected as subjects.All patients underwent magnetic resonance imaging and were divided into myometrium group(lesions involving the myometrium),serous group(lesions located on the serous side of the uterus),and endometrium group(lesions located on the endometrial side)according to lesion location.The pregnancy rate,abortion rate and final live birth rate of the three groups were compared.Results A total of 280 patients were finally included in the study,including 178 in the myometrium group,70 in the serous group and 32 in the endometrium group.The abortion rate in serous group was significantly lower than that in the other two groups(P＜0.05),and the final live birth rate was significantly higher than that in myometrium group and endometrium group(P＜0.05).Binary Logistic regression analysis showed that the risk of miscarriage after IVF-ET in the serous group was lower(OR=0.07,95％CI:0.00-0.62,P=0.014)and the live birth rate was higher(OR=8.38,95％CI:1.47-31.38,P=0.020).Conclusions Adenomyosis lesion location could affect IVF-ET outcome,and evaluation of adenomyosis lesion location could help determine treatment options.
AdenomyosisLesion locationIn vitro fertilization-embryo transfer
万方数据
维普
