Efficacy and safety of filling hyaluronic acid/polylactic acid between penile sarcosus and Buck fascia for penile augmentation:a Meta-analysis
Objective To systematically evaluate the efficacy and safety of filling hyaluronic acid(HA)/polylactic acid(PLA)between penile sarcosus and Buck fascia for penile augmentation.Methods CNKI,Wanfang,CBM,PubMed and Embase database were searched to collect the published clinical studies on HA/PLA filling between penile sarcosus and Buck fascia for penile augmentation.The search period was from the establishment of the database to August 2022.RevMan 5.3 software was used for data processing and Meta-analysis.Results A total of 4 articles with 275 patients were included after screening.Meta-analysis showed that HA or PLA filling between the penile sarcosus and Buck fascia could significantly augment the penis,improved penis appearance and increased sexual satisfaction.Compared with PLA group,HA group had advantages in penile augmentation and sexual satisfaction.The effect of penile augmentation in PLA group was stable,while in HA group,penile circumference decreased with significantly trend.However,there was no statistically significant difference between two groups in improving penile appearance.Conclusions Filling HA or PLA between the penile sarcosus and Buck fascia can significantly augment the penis,improve the appearance of the penis and sexual satisfaction,and the efficacy is safe.Compared with HA,the efficacy of PLA filling is more stable.