Effects of transabdominal approach and extraperitoneal approach with Retzius space preservation on perioperative indicators and postoperative erectile function in patients undergoing laparoscopic radical prostatectomy
Objective To explore the effects of transabdominal approach and extraperitoneal approach with Retzius space preservation on perioperative indicators and postoperative erectile function in patients undergoing laparoscopic radical prostatectomy(LRP).Methods A total of 62 patients with prostate cancer admitted to the First Hospital of Nanping City,Fujian Province from April 2019 to August 2022 were selected as the research subjects.They were divided into transabdominal laparoscopic radical prostatectomy(TLRP)group and extraperitoneal laparoscopic radical prostatectomy(ELRP)group according to the random number table method,with 31 cases in each group.TLRP group received TLRP with Retzius space preservation,and ELRP group received ELRP with Retzius space preservation.Perioperative indicators,postoperative complications,and postoperative erectile function were compared between the two groups.Results The surgical time,intraoperative blood loss,postoperative drainage time,postoperative urinary catheterization time and hospital stay in ELRP group were significantly shorter than those in TLRP group(P<0.05),and there was no statistical difference in the positive rate of incisional margin between the two groups(P>0.05).There were no statistically significant differences in the incidence rates of complications between the two groups(P>0.05).Compared with before surgery,international erectile dysfunction questionnaire-5(IIEF-5)scores in the two groups was both significantly decreased at 3 and 6 months after surgery(P<0.05),and IIEF-5 scores in ELRP group at 3 and 6 months after surgery were significantly higher than those in TLRP group(P<0.05).There was no statistical significance in the incidence rate of erectile dysfunction between the two groups at 6 months after surgery(P>0.05).Conclusions Both ELRP and TLRP with Retzius space preservation can effectively resect the lesions of prostate cancer and alleviate the disease condition,with similar incidence rates of complications.However,ELRP has smaller surgical trauma and faster recovery,and has smaller influence on postoperative erectile function.