首页|疏肝活血法治疗慢性前列腺炎临床疗效的Meta分析

疏肝活血法治疗慢性前列腺炎临床疗效的Meta分析

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目的 综合评价疏肝活血类中药治疗慢性前列腺炎的临床作用,以期为中医药防治慢性前列腺炎提供新思路及可靠依据.方法 检索中国知网、万方数据库、维普数据库、中国生物医学文献数据库、PubMed建库至2023 年2 月收录的采用疏肝活血类中药治疗慢性前列腺炎的临床随机对照试验研究,应用RevMan 5.4 软件对根据纳入排除标准筛选出的 10 篇文献进行Meta分析.结果 Meta结果显示,与单纯使用西药/中成药相比,采用疏肝活血法干预的临床疗效总有效率是对照组的 1.26 倍(RR=1.26,95%CI:1.19~1.34,P<0.000 01);慢性前列腺炎症状指数(NIH-CPSI)评分显著降低(MD=-4.75,95%CI:-5.56~-3.94,P<0.000 01);疼痛(或不适)症状有效缓解(MD =-1.23,95%CI:-1.96~-0.50,P=0.000 9);排尿症状改善(MD=-1.03,95%CI:-1.45~-0.61,P<0.000 01);生活质量提高(MD=-1.18,95%CI:-1.29~-1.07,P<0.000 01).结论 采用疏肝活血类中药治疗慢性前列腺炎,其总有效率、NIP-CPSI评分降低程度、疼痛(或不适)症状的缓解程度、排尿症状的改善及生活质量的提高明显优于单纯应用西药/中成药.
Meta-analysis of the clinical efficacy of Shugan Huoxue Therapy in the treatment of chronic prostatitis
Objective To comprehensively evaluate the clinical effects of traditional Chinese medicine(TCM)herbs of Shugan Huoxue in the treatment of chronic prostatitis,with the aim of providing new ideas and reliable basis for TCM prevention and treatment of chronic prostatitis.Methods The clinical randomized controlled trial studies in the treatment of TCM herbs for Shugan Huoxue were searched in CNKI,Wanfang,VIP,CBM and PubMed from the establishment of the database to February 2023.Meta-analysis of the 10 papers screened in accordance with the inclusion and exclusion criteria was performed with RevMan 5.4 software.Results The Meta results showed that,compared with the use of western/Chinese patent medicine alone,the total effective rate of clinical efficacy of interventions using the Shugan Huoxue Therapy was 1.26 times that of the control group(RR=1.26,95%CI:1.19-1.34,P<0.000,01).The national institute of health chronic prostatitis symptom index(NIH-CPSI)score was significantly reduced(MD =-4.75,95%CI:-5.56--3.94,P<0.000,01).Pain(or discomfort)symptoms was effective mitigated(MD =-1.23,95%CI:-1.96--0.50,P=0.000,9).Urinary symptoms were improved(MD =-1.03,95%CI:-1.45--0.61,P<0.000,01).Quality of life was improved(MD =-1.18,95%CI:-1.29--1.07,P<0.000,01).Conclusions In the treatment of chronic prostatitis,the total effective rate,the reduction of NIP-CPSI score,the relief of pain(or discomfort)symptoms,the improvement of urinary symptoms and the improvement of quality of life were significantly superior in using of TCMherbs of Shugan Huoxue than western/Chinese patent medicine alone.

Shugan HuoxueChronic prostatitisClinical efficacyMeta-analysis

陈颖雯、郑青霞、文证、张泽政、陈树超、傅伟、李其信

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广州中医药大学附属宝安中医院(广州中医药大学第七临床医学院)男科,广东深圳 518133

疏肝活血 慢性前列腺炎 临床疗效 Meta分析

广东省基层老中医药专家传承工作室建设项目广东省科技计划项目

粤中办函[2020]1号2016A020215198

2024

中国性科学
中国性学会

中国性科学

CSTPCD
影响因子:1.394
ISSN:1672-1993
年,卷(期):2024.33(2)
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