Analysis of the distribution characteristics of influencing factors on the miscarriage prevention outcome of pregnant women with early threatened abortion with different vitamin D levels based on latent class analysis method
Objective To analyze the distribution characteristics of influencing factors on the miscarriage prevention outcome of pregnant women with early threatened abortion(TA)with different vitamin D(VD)levels based on the potential latent class analysis(LCA)method.Methods A total of 100 early TA pregnant women admitted to Langfang People's Hospital from January 2021 to September 2022 were selected as the study subjects.They were divided into study group(progesterone+VD)and control group(progesterone)by random number table method,with 50 cases in each group.According to the cluster analysis(CA)results,pregnant women can be divided into two groups,namely high-risk group(n=25,VD≤60 nmol/L)and low-risk group(n=75,VD＞60 nmol/L).The clinical data and the miscarriage prevention outcome of pregnant women were compared and analyzed.Multivariable Logistic regression was used to analyze the risk factors,and LCA was used to explore the distribution characteristics of the influencing factors of fetus protection outcome.Results Compared to the control group,the study group had higher success rate in miscarriage prevention(P＜0.05).Age,number of miscarriages,sleep time,vaginal bleeding volume,treatment methods,VD levels,progesterone(P)levels,and human chorionic gonadotrophin(hCG)levels were all independent influencing factors for failed miscarriage prevention(P＜0.05).There was significant difference in the incidence of failed miscarriage prevention among pregnant women with different levels of VD(P＜0.05).The incidence of failed miscarriage prevention in the high-risk group(60.00％)was significantly higher than that in the low-risk group(13.33％)(P＜0.05).Compared to the low-risk group,the high-risk group had higher proportion of risk factors with more types of distribution(P＜0.05).Conclusions Early pregnancy TA pregnant women with different levels of VD not only have differences in the miscarriage prevention outcome,but also have differences in the distribution characteristics of factors affecting the failed miscarriage prevention between high-risk and low-risk groups.
Latent class analysisVitamin DThreatened abortionOutcomes of miscarriage prevention
万方数据
维普
