Effect and experience of transurethral front-firing greenlight laser enucleation and vaporization in the treatment of large-volume benign prostatic hyperplasia
Objective To explore the safety and efficacy of transurethral front-firing greenlight laser enucleation and vaporization(FFGreenLEVP)in the treatment of large-volume benign prostatic hyperplasia.Methods Clinical data of 52 patients(experimental group)with large-volume benign prostatic hyperplasia who received treatment at the Second Affiliated Hospital of Nanjing Medical University from January 2019 to December 2022 were retrospectively analyzed.The volume of prostate was 80-120 mL,average(88.92±8.37)mL,and FFGreenLEVP was used in treatment of all patients.Operation time,the intraoperative hemoglobin loss,the intraoperative and postoperative complications,the hospitalization time after operation,the postoperative bladder irrigation time,the international prostate symptom score(IPSS),quality of life index(QoL),and maximum urinary flow rate(Qmax)of before and two months after surgery were recorded and analyzed.The above indicators were compared with the clinical data of 31 patients(control group)with large-volume prostatic hyperplasia treated with transurethral resection of the prostate(TURP)from May 2015 to October 2017.Results All the patients treated with FFGreenLEVP successfully completed the surgery.The operation time was(83.10±10.67)min.The mean intraoperative hemoglobin loss was(10.41±1.20)g.The postoperative bladder irrigation time was(1.55±0.63)d.Temporary urinary incontinence was observed in 6 patients,of which 4 patients basically recovered urinary control within 3 days after removing the catheter and 2 patients recovered urinary control one week after removing the catheter.IPSS and QoL two months after operation were significantly lower than those before operation,Qmax was significantly higher than that before operation and the differences were statistically significant(P＜0.01).One month after operation,1 patient developed mild external urethral stricture and was cured after urethral dilation.46 patients were followed up to date without significant recurrence.Compared with the control group,the operation time and postoperative irrigation time were shorter(P＜0.01).There was no significant difference in QoL score,IPSS and Qmax between the two groups 2 months after operation(P＞0.05).Conclusions FFGreenLEVP is safe and effective in treating large-volume benign prostatic hyperplasia and can take advantage of both green laser cutting and vaporization simultaneously.
Benign prostatic hyperplasiaLarge-volumeFront-firing greenlight laserEnucleation of prostateVaporization of prostateTransurethral resection of the prostate
万方数据
维普
