Analysis of sensitivity and specificity of carbohydrate antigen 125,albumin and neutrophil to lymphocyte ratio combined detection in diagnosis of pelvic inflammatory disease
Objective To investigate the sensitivity and specificity of carbohydrate antigen 125(CA125),albumin(Alb),and neutrophil to lymphocyte ratio(NLR)combined detection in diagnosis of pelvic inflammatory disease.Methods A total of 108 patients hospitalized for pelvic inflammatory disease in the Department of Gynecology of Wuhu Traditional Chinese Medicine Hospital from June 2020 to June 2023 were selected as the study group.Additionally,108 healthy women underwent routine health check-ups at the same hospital during the same period were included as the control group.Levels of neutrophils,lymphocytes,Alb,and CA125 were detected,and NLR was calculated in both groups.Pearson correlation analysis was used to assess the relationship between CA125,Alb,and NLR.Receiver operating characteristic(ROC)curves were plotted to analyze the sensitivity and specificity of the three markers for diagnosing pelvic inflammatory disease.Results In the study group,CA125 and NLR levels were higher,while Alb levels were lower compared to the control group,with statistically significant differences(P＜0.05).Pearson correlation analysis showed significant correlations between pairs of CA125,Alb,and NLR(P＜0.05).The area under the curve(AUC)for the combined diagnosis of pelvic inflammatory disease using CA125,Alb,and NLR was higher than that for single detection.Conclusions The combined detection of CA125,Alb,and NLR has high diagnostic value in the diagnosis of pelvic inflammatory disease.
Carbohydrate antigen 125AlbuminNeutrophil to lymphocyte ratioCombined detectionPelvic inflammatory diseaseSensitivitySpecificity
万方数据
维普
