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基于数据挖掘的不射精症证素及用药规律研究

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目的 基于数据挖掘探讨中医药诊疗不射精症的病性、病位、用药规律及组方特点.方法 检索中国知网、万方数据库、维普数据库所收录的建库至2023年4月中医药治疗不射精症的医案、临床研究文献建立数据库,基于古今医案云平台采用数据挖掘技术获取病性、病位证素,对药物进行频数、性味归经、关联规则、聚类分析.结果 共纳入有效文献175篇,涉及方剂283首,中药363味,病性以气滞、气郁、虚证常见,病位以肝、肾为主,用药频次最高为路路通、柴胡、王不留行,性味以平性、温性、寒性为多,归经以肝、肾经为主,关联规则分析9组药对以"柴胡和郁金"药对支持度最高,聚类分析将高频药物分为8类.结论 不射精症虚实结合,实证以"气"为核心,虚证以肾阴虚、肾阳虚为主,治法以通利为主,兼以补肾、疏肝、活血为主.
Data mining-based study on the evidence and medication pattern of anejaculation
Objective To explore the nature of disease,location,medication pattern and the characteristics of the formula in the traditional Chinese medicine(TCM)diagnosis and treatment of anejaculation based on data mining.Methods The medical records and clinical research literatures on TCM treatment of anejaculation were searched from CNKI,Wanfang and VIP from database establishment to April 2023,so as to construct a database.Based on the ancient and modern medical case cloud platform,data mining technology was used to obtain the nature of disease,and location of the disease evidence,the frequency of drugs,flavor attribution,association rules,and clustering analysis were carried out.Results A total of 175 valid literatures were included,involving 283 prescriptions and 363 flavors of traditional Chinese medicine.The nature of disease were common in Qi stagnation,Qi depressions,and deficiency,and the location of the disease was mainly the liver and the kidney.The highest frequency of medication were Lulutong,Chaihu,and Wangbuliuxing.The drug tastes were mostly flat,warm and cold,and the meridians were mainly liver and kidney meridians.In 9 groups of drug pairs analyzed by association rules,the drug pair of"Chaihu and Yujin"had the highest support degree,and the cluster analysis classified the high-frequency drugs into 8 categories.Conclusions The combination of deficiency and solidity of anejaculation.The core of the solid evidence is"Qi",while the deficiency evidence is mainly kidney Yin deficiency and kidney Yang deficiency.The treatment is mainly to pass on the fluids,and to tonify the kidney,dredge the liver and activate the blood at the same time.

AnejaculationTraditional Chinese medical evidenceMedication patternsData mining

陈熙文、蒋艳荣、吴林纳、潘赐明、李青

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云南中医药大学,昆明 650500

天津中医药大学第一附属医院(国家中医针灸临床医学研究中心)针灸科,天津 300193

云南中医药大学第三附属医院老年病科,昆明 650500

不射精症 中医证素 用药规律 数据挖掘

云南省教育厅科研项目研究生项目云南中医药大学大学生创新创业训练计划

2021Y486X2021018

2024

中国性科学
中国性学会

中国性科学

CSTPCD
影响因子:1.394
ISSN:1672-1993
年,卷(期):2024.33(5)
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