Effects of using donor sperm to assist pregnancy in patients with severe oligoasthenozoospermia after failed intracytoplasmic sperm injection on their mental health and erectile function
Objective To explore the effects of using donor sperm to assist pregnancy after intracytoplasmic sperm injection(ICSI)failure in patients with severe oligoasthenozoospermia on their mental health and erectile function,and providing targeted psychological intervention references for this group of people.Methods A total of 410 infertile males severe oligoasthenozoospermia who underwent assisted pregnancy treatment at the Obstetrics and Gynecology Hospital of Tongji University from December 2020 to December 2022 were selected as the research subjects.A total of 68 patients who received donor sperm for assisted pregnancy after ICSI failure were selected as the study group,while 68 patients who continued ICSI assisted pregnancy using a propensity score of 1∶1 were selected as the control group.The general information questionnaire,self-rating anxiety scale(SAS),self-rating depression scale(SDS),Chinese perceived stress scale(CPSS),and international erectile function index-5(IIEF-5)were used to conduct a cross-sectional survey.Total testosterone,mental health,and erectile function status of the two groups were compared.Results There were no significant differences in the social demography data and serum total testosterone levels between the two groups after the propensity score matching(P>0.05).The proportion of individuals with anxiety,depression,and high stress in the study group was higher than those in the control group,and the incidence of erectile dysfunction was higher than that in the control group,the difference is statistically significant(P<0.05).Conclusions The use of donor sperm to assist pregnancy in patients with severe oligoasthenozoospermia after ICSI failure has a significant impact on their mental health and erectile function.Medical staff should pay attention to the mental health and erectile function status of such patients,and develop targeted measures to help them positively respond.
Severe oligoasthenozoospermiaDonor spermErectile functionMental HealthPropensity score