Effects of finasteride combined with transurethral plasmakinetic resection of the prostate on postoperative pain degree and urodynamics in patients with benign prostate hyperplasia
Objective To explore the effects of finasteride combined with transurethral plasmakinetic resection of the prostate on pain degree and urodynamics in patients with benign prostate hyperplasia(BPH).Methods A total of 100 patients with BPH admitted to Huzhou Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical University and the Second Affiliated Hospital of Zhejiang Chinese Medical University from January 2021 to December 2022 were selected as the study objects.They were randomly divided into control group(using transurethral plasmakinetic resection of the prostate)and observation group(using transurethral plasmakinetic resection of the prostate combined with finasteride),with 50 cases in each group.The general surgical indexes,postoperative pain degree,urodynamic indicators and postoperative complication incidence were compared between the two groups.Results The operation duration,urinary tube removal time and hospital stay in the observation group were shorter than those in the control group,and the intraoperative blood loss was less than that in the control group,with the statistically significant differences(P<0.05).After operation,the pain degree of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05).The incidence of complications in the observation group was lower than that in the control group,but the difference was not statistically significant(P>0.05).After 6 months of operation,postvoid residual(PVR)level decreased in both groups,and the value in the observation group was lower than that in the control group,the maximum urinary flow rate(Qmax)and bladder compliance(BC)levels increased in both groups,and the value in the observation group was higher than that in the control group,with statistically significant differences(P<0.05).Conclusions Finasteride combined with transurethral plasmakinetic resection of the prostate have good clinical effects on treating BPH,with shorter operative duration,shorter urinary tube removal time,shorter hospital stay,and fewer intraoperative blood loss.It can effectively reduce postoperative pain,reduce PVR volume,and increase Qmax and BC.
FinasterideTransurethral plasmakinetic resection of prostateBenign prostate hyperplasiaPain degreeUrodynamic indicators