Effects of robot-assisted minimally invasive surgery on anastomotic urinary leakage,third space effect and cell adhesion molecules in patients with prostate cancer
Objective To investigate the effects of robot-assisted minimally invasive surgery on anastomotic urinary leakage,third space effect and cell adhesion molecules in patients with prostate cancer(PCa).Methods A total of 80 patients with PCa admitted to Panzhihua Central Hospital from January 2019 to October 2021 were selected as study objects.They were divided to study group and control group by random number table,with 40 cases in each group.The control group underwent laparoscopic radical prostatectomy(LRP),while the study group underwent robot-assisted minimally invasive surgery.The surgical-related conditions,the third space effect[sodium ion(Na+),potassium ion(K+),calcium ion(Ca2+)],adhesion molecules[soluble differentiation anti-44 molecule variant 6(sCD44v6),soluble vascular cell adhesion molecule(sVCAM-1)]before and after surgery in two groups were compared,as well as complications and urinary control at 12 months after surgery.Results The intraoperative blood loss and blood transfusion rate in the study group were lower than those in the control group(P＜0.05).The serum Na+and Ca2+of two groups showed a decrease and then increase trend from before to 5 days after surgery,and the serum K+and the plasma levels of sVCAM-1 and sCD44v6 showed a increase and then decrease trend(P＜0.05).There were no significant differences in the incidence of complications and recovery condition of urinary control between two groups(P＞0.05).Conclusions The short-term effect of robot-assisted minimally invasive surgery for PCa patients is similar to that of laparoscopic radical surgery,but the intraoperative blood loss is low and blood transfusion can be reduced.
万方数据
维普
