Research progress on stem cell therapy for thin endometrium
The thickness of the endometrium is a widely-recognized indicator of uterine receptivity.An excessively thin endometrium not only leads to irregular menstruation in women but also decreases the embryo implantation rate and live birth rate among women of childbearing age.Moreover,it stands as a significant cause for the cancellation of assisted reproductive cycles.While numerous methods exist for treating thin endometrium,there are currently no definitive consensus or guideline.In recent years,stem cells have become the focus of multidisciplinary research due to their capacity for infinite self-renewal,proliferation and differentiation into diverse cell types.The utilization of stem cells to repair damaged endometrium has emerged as a new avenue.Transplanting stem cells from various sources,including menstrual blood,bone marrow,umbilical cord,placenta,and adipose tissue,has shown efficacy in promoting endometrial regeneration and recovery,thereby enhancing endometrial function.This paper provides an analysis of recent application progress of stem cell therapy for thin endometrium and the pros and cons of stem cell clinical treatment,aiming to offer insights for future clinical treatments and research innovations.
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