Pregnancy following in vitro fertilization-embryo transfer complicated with congenital osteogenesis imperfecta by cesarean section:a case report and literature review
Congenital osteogenesis imperfecta is a rare congenital bone development disorder and the main clinical manifestations are repeated brittleness fracture,skeletal deformity and short stature.Pregnancy complicated with congenital osteogenesis imperfecta is extremely rare.The key of treatment is to ensure the safety of the pregnant woman and fetus during pregnancy and perinatal period.This paper reports a case of pregnancy following in vitro fertilization-embryo transfer complicated with congenital osteogenesis imperfecta admitted in the First Hospital of Lanzhou University.This patient,with skeletal deformity and short stature,presented compression symptoms due to uterine enlargement at 34 weeks of gestation and was admitted to hospital.After multidisciplinary team discussion,it was decided to terminate the pregnancy.The possible intraoperative and postoperative complications were fully evaluated before surgery,and the corresponding preventive measures were taken.Then,under tracheal intubation general anesthesia,lower uterine section caesarean section was performed to aid delivery of an immature girl in head position.In this case,due to adequate preoperative preparation,the operation went smoothly and the mother and baby recovered well after the operation.By reporting this case and reviewing the literature,the researchers can deepen the understanding of this disease and improve the clinical diagnosis and treatment ability.
In vitro fertilization-embryo transferPregnancyCongenital costeogenesis imperfectaCesarean section