首页|体外受精-胚胎移植后妊娠合并先天性成骨不全经剖宫产1例并文献复习

体外受精-胚胎移植后妊娠合并先天性成骨不全经剖宫产1例并文献复习

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先天性成骨不全是一种罕见的先天性骨骼发育障碍性疾病,主要临床表现为反复脆性骨折、骨骼畸形和身材矮小.妊娠合并先天性成骨不全极其罕见,处理关键是保证妊娠期、围产期母体和胎儿的安全.本文报告1例兰州大学第一医院收治的体外受精-胚胎移植后妊娠合并先天性成骨不全病例情况,该患者骨骼畸形、身材矮小,孕34周因宫体增大出现压迫症状收住入院,经多学科会诊讨论后决定终止妊娠,术前充分评估了术中、术后可能发生的并发症,并做了相应的预防措施,后于气管插管全麻下行子宫下段剖宫产术,以头位助娩1名发育欠成熟女婴.本例术前准备充分,术程顺利,术后母婴恢复良好.通过对该病例情况的报告,并回顾文献资料,加深对该疾病的认识,进而提高临床诊治能力.
Pregnancy following in vitro fertilization-embryo transfer complicated with congenital osteogenesis imperfecta by cesarean section:a case report and literature review
Congenital osteogenesis imperfecta is a rare congenital bone development disorder and the main clinical manifestations are repeated brittleness fracture,skeletal deformity and short stature.Pregnancy complicated with congenital osteogenesis imperfecta is extremely rare.The key of treatment is to ensure the safety of the pregnant woman and fetus during pregnancy and perinatal period.This paper reports a case of pregnancy following in vitro fertilization-embryo transfer complicated with congenital osteogenesis imperfecta admitted in the First Hospital of Lanzhou University.This patient,with skeletal deformity and short stature,presented compression symptoms due to uterine enlargement at 34 weeks of gestation and was admitted to hospital.After multidisciplinary team discussion,it was decided to terminate the pregnancy.The possible intraoperative and postoperative complications were fully evaluated before surgery,and the corresponding preventive measures were taken.Then,under tracheal intubation general anesthesia,lower uterine section caesarean section was performed to aid delivery of an immature girl in head position.In this case,due to adequate preoperative preparation,the operation went smoothly and the mother and baby recovered well after the operation.By reporting this case and reviewing the literature,the researchers can deepen the understanding of this disease and improve the clinical diagnosis and treatment ability.

In vitro fertilization-embryo transferPregnancyCongenital costeogenesis imperfectaCesarean section

王黎、杨永秀

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兰州大学第一临床医学院,兰州 730000

兰州大学第一医院妇产科,兰州 730000

体外受精-胚胎移植 妊娠 先天性成骨不全 剖宫产

甘肃省自然科学基金

20JR10RA693

2024

中国性科学
中国性学会

中国性科学

CSTPCD
影响因子:1.394
ISSN:1672-1993
年,卷(期):2024.33(9)
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