Logistic regression analysis of human papilloma virus infection status and high-risk human papilloma virus persistent infection in women with cervical cancer prevention screening in outpatient department
Objective To explore the human papilloma virus(HPV)infection status and risk factors of persistent infection of high-risk human papilloma virus(HR-HPV)in women with cervical cancer screening in outpatient department.Methods A total of 340 women who received cervical cancer screening in Dongyang Maternal and Child Health Hospital,Zhejiang Province from January 2021 to December 2022 were selected as the study subjects.According to whether HPV infection occurred,they were divided into HPV infection group(n=72)and HPV non-infection group(n=268).The HPV infection status and risk factors of HR-HPV persistent infection were analyzed.Results There were 72 cases(21.18％)of HPV infection,55 cases(76.38％)of single HPV subtype infection and 17 cases(23.61％)of multiple infection.Among the 72 patients with HPV infection,17 cases(23.61％)were with persistent infection,including 11 cases(64.71％)of HR-HPV persistent infection.Women with age ≥35 years,number of pregnancies＞twice,age of first sexual intercourse＜25 years old,sexual frequency＞5 times/month,cervical vaginal inflammation,number of sexual partners＞2,contraceptive method of oral contraceptives,and no hygienic habits after intercourse had higher HR-HPV persistent infection rate(P＜0.05).Age≥35 years old,number of pregnancies＞twice,cervical vaginal inflammation and contraceptive method of oral contraceptives were risk factors for HR-HPV persistent infection in women undergoing cervical cancer prevention screening(P＜0.05).Conclusions The proportion of HPV infection in female cervical cancer screening is relatively high.The risk of HR-HPV persistent infection is higher in women with older age,more pregnancies,cervical vaginal inflammation and contraceptive method of oral contraceptives.
Cervical cancer screeningHuman papilloma virusPersistent infectionRisk factors
万方数据
维普
