首页|补肾生精法治疗特发性少、弱精子症的Meta分析

补肾生精法治疗特发性少、弱精子症的Meta分析

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目的 应用Meta分析研究补肾生精法治疗特发性少、弱精子症的疗效.方法 检索中国知网、维普、万方、中国生物医学文献数据库、PubMed等数据库建库至2023年10月收录的采用补肾生精法治疗特发性少、弱精子症的临床随机对照试验文献.运用方法学质量评价,使用RevMan 5.4软件进行统计分析,并进行偏倚分析.结果 共纳入7篇文献.Meta分析结果显示:采用补肾生精法治疗特发性少、弱精子症患者的总有效率(RR=1.26,95%CI:1.10~1.43,P=0.000 6)、精子密度(WMD=23.83,95%CI:21.87~25.78,P<0.000 01)、配偶妊娠率(RR=1.89,95%CI:1.56~2.29,P<0.000 01)均显著优于对照组.结论 补肾生精法治疗特发性少、弱精子症具有较好的临床疗效,可以显著提高精子密度、精子活动率及配偶妊娠率,且无明显不良反应报道,安全性及有效性均较高.
Meta-analysis on the treatment of idiopathic oligospermia and asthenospermia by tonifying kidney and promoting sperm method
Objective To study the therapeutic effect of tonifying kidney and promoting sperm method on idiopathic oligospermia and asthenospermia by Meta-analysis.Methods The clinical randomized controlled trials of treating idiopathic oligospermia and asthenospermia by tonifying kidney and promoting sperm method included in CNKI,VIP,Wanfang,China Biology Medicine,and PubMed from database establishment to October 2023 were searched.Methodological quality evaluation was used,statistical analysis was carried out by using RevMan 5.4 software,and bias analysis was performed.Results A total of 7 papers were included.The Meta-analysis results show that:the total effective rate of idiopathic oligozoospermia(RR=1.26,95%CI:1.10-1.43,P=0.000,6),sperm density(WMD=23.83,95%CI:21.87-25.78,P<0.000,01),and spouse pregnancy rate(RR=1.89,95%CI:1.56-2.29,P<0.000,01)in idiopathic oligospermia and asthenospermia patients treated by tonifying kidney and promoting sperm method were significantly better than control group.Conclusions The tonifying kidney and promoting sperm method has a good clinical therapeutic effect on idiopathic oligospermia and asthenospermia,it can significantly improve sperm density,motility and spouse pregnancy rate,and no obvious adverse reaction is reported,with high safety and efficacy.

Tonifying kidney and promoting sperm methodOligospermiaAsthenospermiaMale infertilityMeta-analysis

林美欣、傅伟、游旭军、丁劲、李其信、远庚彦

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广州中医药大学第七临床医学院,广东 深圳 518133

补肾生精法 少精子症 弱精子症 男性不育 Meta分析

中药医院制剂研发专项深圳市宝安中医院资助项目

2022KJCX-YYZJ-6BAZYY20200610

2024

中国性科学
中国性学会

中国性科学

CSTPCD
影响因子:1.394
ISSN:1672-1993
年,卷(期):2024.33(10)