首页|基于数据挖掘探讨师伟教授治疗多囊卵巢综合征的用药规律

基于数据挖掘探讨师伟教授治疗多囊卵巢综合征的用药规律

扫码查看
目的 基于数据挖掘探讨师伟教授治疗多囊卵巢综合征(PCOS)的用药规律.方法 获取2020年1月1日至2023年9月30日在山东中医药大学附属医院妇科师伟主任门诊就诊的符合PCOS诊断标准的患者的中药处方.运用Microsoft Excel 2010进行数据管理,运用SPSS Modeler 18.0进行高频药物关联规则和复杂网络分析,运用SPSS Statistics 25.0进行系统聚类分析.结果 共纳入262首中药处方,涉及88味中药,用药频次共计5 960次.其中,高频中药(频次>100次)共计28味,排名前5的中药分别是甘草、当归、陈皮、益母草、白术;药性以温性居多,药味以甘、辛、苦为主,归经以肝、脾、肾经为主,功效以补虚药、理气药、活血化瘀药为主;系统聚类得到5个药物组合,复杂网络分析得到1个核心药物组合.结论 师伟教授治疗PCOS以燮理脏腑阴阳、调和冲任气血为治疗原则,以补肾通阳、健脾消痰、疏肝解郁为基本治法.
Discussion on medication rules of professor Shi Wei in the treatment of polycystic ovary syndrome based on data mining
Objective To discuss medication rules of professor Shi Wei in the treatment of polycystic ovary syndrome(PCOS)based on data mining.Methods Traditional Chinese medicine(TCM)prescriptions for patients admitted to outpatient clinic of director Shi Wei from the Department of Gynecology of the Affiliated Hospital of Shandong University of Traditional Chinese Medicine from January 1,2020 to September 30,2023 and met the diagnostic criteria of PCOS were obtained.Microsoft Excel 2010 was used for data management.SPSS Modeler 18.0 was used for high-frequency drug association rule and complex network analysis,and SPSS Statistics 25.0 was used for systematic cluster analysis.Results A total of 262 TCM prescriptions were included,involving 88 kinds of TCM herbal medicines.The total frequency of medication was 5,960 times.Among them,there were 28 high-frequency TCM herbs(frequency>100 times),and the top 5 were licorice,angelica sinensis,tangerine peel,motherwort,and atractylodes macrocephala.The medicinal properties were mostly warm,with the main flavors being sweet,spicy,and bitter.The meridians were mainly liver,spleen,and kidney,and the main effects were tonifying deficiency,regulating Qi,and promoting blood circulation and removing stasis.5 clusters of drug combinations were obtained through systematic cluster,and 1 core drug combination was obtained from complex network analysis.Conclusions The treatment of PCOS by professor Shi Wei is based on the treatment principles of regulating the Yin and Yang of the organs,and harmonizing the Qi and blood of Chongren,with the basic treatment methods of tonifying the kidney and promoting Yang,strengthening the spleen and reducing phlegm,and soothing the liver and relieving depression.

Data miningProfessor Shi WeiPolycystic ovary syndromeMedication rules

张全英、刘洋、张一诺、陈一诺、师伟

展开 >

山东中医药大学第一临床医学院,济南 250014

安徽省阜阳市第六人民医院中医科,安徽阜阳 236015

天津中医药大学研究生院,天津 301617

山东中医药大学附属医院妇科,济南 250014

展开 >

数据挖掘 师伟教授 多囊卵巢综合征 用药规律

2024

中国性科学
中国性学会

中国性科学

CSTPCD
影响因子:1.394
ISSN:1672-1993
年,卷(期):2024.33(12)