Analysis of clinical medication rule of traditional Chinese medicine for genital herpes based on data mining
Objective To analyze the clinical medication rule and characteristics of traditional Chinese medicine(TCM)in treating genital herpes(GH)by data mining.Methods Collect and sort out the literature on the treatment of GH with TCM from 1990 to 2023 from CNKI,Wanfang,VIP,and CBM disc were collected to build a standardized database of prescriptions.Association rule analysis and system cluster analysis were used to study the rule of drug use,and frequency statistics on the drugs and their properties,tastes,and meridians were carried out.Results A total of 320 articles were included,with 229 drugs used.Oral and external drugs both mainly included heat-clearing drugs,tonic drugs,and diuretic dampness-removing water drugs.The external drugs were mainly cold,while the oral drugs contained cold and warm.Both drugs were mainly sweet and bitter in taste,and the meridian tropism was mainly liver,lung,spleen,and stomach meridians.Oral drug(≥79 frequencies)association rule analysis obtained 12 two-item associations rule combination and 3 three-item associations rule combination,and cluster analysis obtained 4 core combinations.External drug(≥9 frequencies)association rule analysis obtained 3 two-item associations rule combination and 5 three-item associations rule combination,and cluster analysis obtained 3 core combinations.Conclusions The prescription of TCM for treating GH mainly consists of heat-clearing drugs,tonic drugs and diuretic dampness-removing drugs.
Genital herpesTraditional Chinese medicineData miningMedication rules