Analysis of the prevalence rate of dyslipidemia and hyperglycemia in human immunodeficiency virus/acquired immunodeficiency syndrome patients and its influencing factors
Objective To investigate the prevalence rate of dyslipidemia and hyperglycemia in human immunodeficiency virus/acquired immunodeficiency syndrome(HIV/AIDS)patients and its influencing factors.Methods The basic demographic characteristics and laboratory data of HIV/AIDS patients initially treated in the Clinic of Department of Infection Diseases,Dali Bai Autonomous Prefecture People's Hospital in 2011 were collected,and the prevalence rate of dyslipidemia,hyperglycemia and its influencing factors were analyzed.Results A total of 156 HIV/AIDS patients with a mean age of(38.6±9.6)years were enrolled.Before antiretroviral therapy(ART),the prevalence rate of dyslipidemia was 49.4％,hypertriglyceridemia was 42.3％,hypercholesterolemia was 12.2％,and hyperglycemia was 12.2％.After ART,the prevalence rate of dyslipidemia was 93.6％,hypertriglyceridemia was 89.1％,hypercholesterolemia was 73.1％,and hyperglycemia was 51.9％.Multivariate Logistic regression analysis showed that male HIV/AIDS patients had a greater risk of hypertriglyceridemia(P＜0.05).HIV/AIDS patients infected through sexual transmission were more likely to develop hypercholesterolemia(P＜0.05).HIV/AIDS patients with age ≥45 years and hepatitis C virus(HCV)infection were independent risk factors for hyperglycemia(P＜0.05).Conclusions The prevalence rate of dyslipidemia and hyperglycemia in initially treated HIV/AIDS patients was high,and the prevalence rate of dyslipidemia and hyperglycemia was further increased after receiving ART.Male HIV/AIDS patients are more prone to dyslipidemia,and the risk factors for hyperglycemia are mainly age≥45 years and combined with HCV infection.During the follow-up process,routine monitoring of blood lipids and blood glucose changes should be carried out in order to early intervention.
Human immunodeficiency virusAcquired immunodeficiency syndromeAbnormal blood lipidsHyperglycemiaInfluencing factor
万方数据
维普
