基于胃肠道菌群探讨奶牛乳腺炎发生和调控的机制
Study on the Pathogenesis and Regulation of Mastitis in Dairy Cows Based on Gastrointestinal Flora
袁利平 1张宁宁 2谢红兵 1张坤 1常美楠 1夏小静 1贺永惠 1滕战伟1
作者信息
- 1. 河南科技学院动物科技学院,河南新乡 453003
- 2. 河南科技学院动物科技学院,河南新乡 453003;河南科技学院国际教育学院,河南新乡 453003
- 折叠
摘要
奶牛乳腺炎发病率高,给奶牛业发展和消费者健康造成了巨大危害.传统观念认为,乳腺炎是细菌等病原微生物感染乳腺引起的局部炎症反应.但生产实践中发现,奶牛采食高精料日粮可引起胃肠道菌群紊乱,导致奶牛乳腺炎发病率升高,从而影响奶牛乳腺健康.这表明奶牛乳腺炎的发生除与外源性病原微生物感染有关外,还存在内源性致病途径.本文综述了奶牛乳腺炎的致病因素和发病机制、胃肠道微生物与奶牛产奶效率的关系、胃肠道菌群影响乳腺炎发生的机制及调控措施,为奶牛乳腺炎的防治提供新的视角和机遇,进而促进奶牛业持续健康发展.
Abstract
The high incidence rate of mastitis in dairy cow has caused great harm to the development of dairy industry and the health of consumers.Traditionally,mastitis is the local inflammatory reaction that infected by pathogenic microorganisms to mammary gland.However,it was found in production practice that high-concentrate diet could cause gastrointestinal flora disorder and increase the incidence rate of cow mastitis in dairy cows,which would affect the health of cow mammary glands.This indicates that the occurrence of cow mastitis is not only associated with the infection of exogenous pathogenic microorganisms,but also there is an endogenous pathogenic pathway.Therefore,this paper summarizes the pathogenic factors and pathogenesis of mastitis in dairy cows,the relationship between gastrointestinal microorganisms and milk production efficiency in dairy cows,the mechanism and control measures of gastrointestinal flora affecting the occurrence of mastitis,providing a new perspective and opportunity for the prevention and treatment of mastitis in dairy cows,and promoting the sustainable and healthy development of dairy industry.
关键词
奶牛/胃肠道菌群/产奶效率/血乳屏障/乳腺炎Key words
Dairy cow/Gastrointestinal microbiota/Milk production efficiency/Blood-milk barrier/Mastitis引用本文复制引用
基金项目
国家自然科学基金(32172876)
国家自然科学基金(32302798)
河南省高等学校重点科研项目(23A230007)
河南省重点研发与推广专项(科技攻关)项目(202102110087)
河南省重点研发与推广专项(科技攻关)项目(232102111049)
河南科技学院人才引进项目(103020222001/009)
出版年
2024
国家科技期刊平台
NSTL
万方数据