The rumen of calves is not yet fully developed,and the digestive tract is relatively fragile,making their digestive tract relatively fragile and prone to infection by pathogenic bacteria,which can cause diarrhea in calves.Lactic acid bacteria and yeast have good acid resistance and antibacterial properties,which can improve the intestinal environment of calves,promote the colonization of beneficial bacteria,strengthening the immunity of the gastrointestinal mucosa of calves,and thereby improve the growth performance of calves.This article mainly reviews the research progress of lactic acid bacteria and yeast microbial preparations that can affect the gastrointestinal health of calves in recent years,with the aim of providing a theoretical basis for the use of lactic acid bacteria and yeast microbial preparations in the feeding process of calves.