Under the background of the normalization of African swine fever,China's pig breeding is now in a period of rapid transformation.The total number of farmers is gradually decreasing,but large-scale breeding has increased.The industrialization and process management needs of pig production are increasingly urgent,and the batch production management system has been widely recognized and applied.Altrenogest,also known as tetraenoestrone,is a progestogen analogue that can effectively inhibit the release of gonadotropins,thereby inhibiting estrus and achieving the effect of synchronizing the estrous cycle,and has been widely used in gilts to come into heat at the same time.However,the role of altrenogest in pregnancy regulation and improvement of uterine environment has not been fully recognized and exerted.In this paper,the mechanism of action of altrenogest and the dosage scheme and effects on sows at different stages are reviewed,and the problems and prospects of altrenogest in practical production and application are discussed,in order to provide a reference for intensive study of the new application of altrenogest in the regulation of sow reproduction and production.