Advances in the Effects and Mechanisms of Adiponectin on Hepatic Steatosis in Animals
Adiponectin is a kind of cytokines that can regulate lipid metabolism disorder,increase insulin sensitivity,improve liver fat accumulation and other physiological and pathological processes of liver steatosis.Animal liver steatosis is the accumulation of lipids due to the abnormal pathway of fatty acid intake or synthesis,reduction of fatty acid oxidation,insulin resistance and inflammatory response in the liver.This review article introduces the pathogenesis and pathogenesis of animal liver steatosis,and focuses on the effects of adiponectin on animal liver steatosis through AMPK signaling pathway and PPARα signaling pathway and the mechanism.The application prospect of adiponectin as a new target for the prevention and treatment of fatty liver diseases in animals and a reference index for clinical diagnosis was prospected,in order to provide reference for the application of adiponectin in the prevention and treatment of animal fatty liver disease.
国家科技期刊平台
NSTL
万方数据
