Research Progress on the Regulation Mechanism of Wnt Signaling Pathway in Hair Follicle Genesis and Periodic Development
Animal hair follicle development goes through three periods:anagen,catagen and telogen,and each period is precisely regulated by different signaling molecules.Many studies have shown that the Wnt signaling pathway not only directly regulates the formation and cycling of hair follicles,but also indirectly regulates the development of hair follicles through cross-linking with other signaling pathways.The aim of this paper is to review the biological properties of mammalian hair follicles,the regulatory role of the Wnt signaling pathway in hair follicle development and its interactions with other pathways,and then to find new ways to improve the quality of hair and increase production.This is of great economic importance to the wool,textile and tanning industries.
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