Dysprosium oxide,alumina,and graphene oxide reinforced polycaprolactone thin films:Thermal stability,morphology,and cell viability

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外文摘要：Developing a biomaterial for wound healing applications is still a challenge.Herein,dysprosium oxide(Dy2O3),aluminum oxide(Al2O3),and graphene oxide(GO)were embedded in cast films based on polycaprolactone(PCL)to be examined for wound dressing usage.Different techniques were used to characterize the fabricated films including X-ray diffraction(XRD),Fourier transform infrared spectros-copy(FTIR),Raman,and scanning electron microscopy(SEM),besides their biological activity.The thermogravimetric analysis(TGA)exhibits high thermal stability as the scaffold weight decreases slightly to 98.6％after raising the temperature from room temperature to 280 ℃.The cell viability was investi-gated and it is shown that the viable cells grow up to approximately 93％at 75 μg/mL.Meanwhile,the cell attachment shows excellent behavior as the cells attach on most of the surface of the modified PCL which shows high biocompatibility.

外文关键词：

Wound healingPolycaprolactoneDy2O3Al2O3BiocompatibleRare earths

作者：

Mohamed Tharwat Elabbasy、Mohamed R.Atteya、Mai A.Samak、Mousa Abdelrahman、Tahani AlMahmoud、M.A. El-Morsy、A.A. Menazea、M.F.H. Abd El-Kader

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作者单位：

Department of Public Health,College of Public Health and Health Informatics,University of Ha'il,Ha'il,2440,Saudi Arabia

Food Control Department,Faculty of Veterinary Medicine,Zagazig University,Zagazig,44519,Egypt

Department of Physical Therapy,College of Applied Medical Sciences,University of Ha'il,Ha'il,Saudi Arabia

Department of Histology and Cell Biology,Faculty of Medicine,Zagazig University,Zagazig,44519,Egypt

College of Nursing,University of Ha'il,Ha'il,Saudi Arabia

College of Science and Humanities in Al-Kharj,Physics Department,Plasma Technology and Material Science Unit,Prince Sattam Bin Abdulaziz University,Al-kharj,11942,Saudi Arabia

Physics Department,Faculty of Science,University of Damietta,New Damietta,34517,Egypt

Spectroscopy Department,Physics Research Institute,National Research Centre,Dokki,12622,Giza,Egypt

Biophysics Department,Faculty of Science,Cairo University,Giza,Egypt

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基金：

Scientific Research Deanship at University of Ha'il,Saudi Arabia

项目编号：

RG-20-222

出版年：

2024

DOI：

10.1016/j.jre.2023.08.013