首页|失眠障碍患者睡眠脑电分型与治疗研究进展

失眠障碍患者睡眠脑电分型与治疗研究进展

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失眠障碍是一种临床常见的精神障碍.目前失眠障碍的临床分型主要依据临床症状描述,缺乏客观检测依据,治疗循证基础薄弱.近年来,睡眠脑电对于观察患者睡眠结构和连续性的异常日益受到重视,有助于探索失眠障碍的生物机制,有利于临床精准分型并提升个性化治疗水平.本文着重综述失眠障碍的睡眠脑电亚型的五种分型,包括基于客观睡眠时间、功率频谱特征、循环交替模式、纺锤波和微觉醒的分型并说明各亚型与临床转归关联的特点,旨在为失眠障碍的临床分型和个性化治疗提供循证依据.
Advances on sleep electroencephalogram in the subtyping and treatment of insomnia disorder
Insomnia disorder is a common clinical mental disorder.Currently,clinical subtyping of insomnia disorder relies primarily on symptomatic descriptions,lacking objective measures and subtyping-based treatment approaches.In recent years,increasing attention has been drawn to sleep electroencephalo-graphy(EEG)as a valuable tool for observing abnormal sleep architecture and continuity of insomnia disor-der.Sleep EEG analysis holds the potential to elucidate the underlying biological mechanisms of insomnia disorder,facilitating data-driven subtyping and enhancing personalized therapeutic strategies.Five types of sleep EEG subtypes of insomnia disorder were systematically searched and summarized:classifications de-rived from objective sleep duration,power spectral characteristics,cyclic alternating pattern,spindle and mi-croarousal.EEG characteristics of each subtype and clinical outcomes are discussed.This review aims to pro-vide evidence-based insights for clinical subtyping and personalized treatment of insomnia disorder.

Insomnia disorderSleep electroencephalogramSleep structureSubtypingTreatmentOutcome

吕洞宾、张毓、苑成梅、张天宏、肖泽萍

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上海交通大学医学院附属精神卫生中心,上海 200030

失眠障碍 睡眠脑电 睡眠结构 分型 治疗 转归结局

国家自然科学基金上海市申康发展中心重大临床研究项目上海市科委科技创新行动计划

81971261SHDC2020CR407420Y11906600

2024

中华行为医学与脑科学杂志
中华医学会 济宁医学院

中华行为医学与脑科学杂志

CSTPCD北大核心
影响因子:1.472
ISSN:1674-6554
年,卷(期):2024.33(1)
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