Current status and influencing factors of cognitive function among elderly residents in Qingdao city
Objective To investigate the cognitive function and its influencing factors among resi-dents in Qingdao city.Methods The 5 311 research subjects over 65 years old were selected from Qingdao by simple random sampling and stratified sampling.All subjects were investigated by AD8 dementia early screening questionnaire and community screening instrument dementia(CSI-D)to evaluate the prevalence of cognitive decline in this study.The score of AD8 dementia early screening questionnaire ≥ 2 points or the score of CSI-D ≤ 7 points was considered to be cognitive decline.Mann-Whitney U test,Chi-square test,Fisher exact probability method,univariate and multivariate Logistic regression analysis and Bootstrap verifi-cation were performed using SPSS 26.0 software.Results Among 5 311 subjects,1 899 subjects had nor-mal cognitive function(35.76％)and 3 412 subjects had cognitive decline(64.24％).The age of the cog-nitive decline group was significantly higher than that of the normal group(P＜0.01).There were significant differences in gender,educational level,rural residents,marital status,chronic medical history,hypertension,rheumatoid arthritis,cerebrovascular disease,intervertebral disc disease,ischemic heart disease,monthly household income and alcohol consumption between the two groups(all P＜0.05).Univariate Logistic re-gression analysis showed that female(β=0.313,OR=1.367,95％CI=1.221-1.530),age(β=0.052,OR=1.053,95％CI=1.043-1.063),rural residents(β=0.850,OR=2.340,95％CI=2.042-2.682),widowed(β=0.557,OR=1.745,95％CI=1.500-2.029),chronic medical history(β=0.290,OR=1.336,95％CI=1.191-1.498),hypertension(β=0.134,OR=1.143,95％CI=1.020-1.281),rheumatoid arthritis(β=0.458,OR=1.581,95％CI=1.222-2.046),cerebrovascular disease(β=0.584,OR=1.794,95％CI=1.352-2.380),intervertebral disc disease(β=0.578,OR=1.782,95％CI=1.370-2.319),ischemic heart disease(β=0.501,OR=1.651,95％CI=1.272-2.143)were the risk factors for cognitive decline.Higher education level,higher monthly household income and abstinence(β=-0.244,OR=0.783,95％CI=0.619-0.992)were protective factors for cognitive decline.Multivariate logistic regression analysis showed that age(β=0.035,OR=1.036,95％CI=1.025-1.047),rural residents(β=0.215,OR=1.239,95％CI=1.047-1.468),chronic medical history(β=0.191,OR=1.210,95％CI=1.067-1.372),cerebrovascular disease(β=0.480,OR=1.616,95％CI=1.195-2.187),intervertebral disc disease(β=0.456,OR=1.578,95％CI=1.190-2.094)were risk factors for Alzheimer's disease.Higher education level and higher monthly house-hold income were protective factors for Alzheimer's disease.Conclusion The elderly with chronic diseases,low income and low education level may be at the high risk of cognitive function decline,which should be paid attention to in early screening and intervention.
Cognitive function declineRisk factorElderlyLogistic regression analysisBootstrap analysis
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