Effects of variable priority cognitive-motor dual-task training in aged cognitive frailty patients with type 2 diabetes mellitus
Objective To explore the effect of variable priority cognitive-motor dual-task training in aged cognitive frailty patients with type 2 diabetes mellitus.Methods From September 2022 to September 2023,a total of 108 aged cognitive frailty patients with type 2 diabetes mellitus were selected in the Depart-ment of Endocrinology of North China University of Science and Technology Affiliated Hospital as research subjects.The subjects were divided into three groups in the order of admission,with 36 people in each group.Three groups of patients were intervened for 8 weeks using variable priority cognitive-motor dual-task training(VP group),exercise combined cognitive intervention with sequential task(ST group),and endocrinology routine treatment and nursing(control group),respectively.The scores of mini-mental state examination(MMSE),frailty phenotype(FP)and Berg balance scale(BBS)were compared among the three groups be-fore and after the intervention.Repeated measurement variance analysis was used to compare scale results by SPSS 22.0.Results(1)The MMSE score of patients before and after intervention had significant interac-tion effect between time and groups(F=69.929,P＜0.05).The MMSE scores of the VP group and ST group after 8 weeks of intervention were higher than those before intervention and after 4 weeks of intervention,and the MMSE scores of the two groups after 4 weeks of intervention were also higher than those before interven-tion(all P＜0.05).After 4 weeks and 8 weeks of intervention,the MMSE score of the VP group was higher than that of the ST group and the control group,and the MMSE score of the ST group was higher than that of the control group after 8 weeks of intervention(all P＜0.05).(2)The FP score of patients before and after in-tervention had a significant interaction effect between time and groups(F=46.425,P＜0.05).The FP score of the VP group at 8 weeks of intervention(2.64±0.59)was lower than that after 4 weeks of intervention(3.28±0.51)and before intervention(3.56±0.61),and the FP score after 4 weeks of intervention was lower than before intervention(all P＜0.05).The FP score of the ST group after 8 weeks of intervention(3.44±0.56)was lower than before the intervention(3.59±0.56)(P＜0.05);After 4 weeks of interven-tion,the FP score of the VP group was lower than that of the control group(3.36±0.54)(P＜0.05).After 8 weeks of intervention,the FP score of the VP group was lower than that of the ST group and the control group(3.39±0.55)(both P＜0.05).(3)The FP score of patients before and after intervention had a significant interaction effect between time and groups(F=135.791,P＜0.05).The BBS scores of the VP group and ST group after 8 weeks of intervention were higher than those before and after 4 weeks of intervention,and the BBS scores after 4 weeks of intervention were also higher than those before intervention(all P＜0.05).After 4 weeks of intervention,the BBS score of the VP group was higher than that of the control group(P＜0.05).After 8 weeks of intervention,the BBS score of the VP group was higher than that of the ST group and the control group,and the BBS score of the ST group was also higher than that of the control group(all P＜0.05).Conclusion The variable priority cognitive-motor dual-task training can improve the cognitive func-tion,physical frailty and balance function in aged cognitive frailty patients with type 2 diabetes mellitus,and the intervention effect is better than that of exercise combined cognitive intervention with sequential task and endocrinology routine treatment and nursing.
Type 2 diabetes mellitusCognitive frailtyDual taskVariable priorityAged
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