摘要
目的 探讨社区老年人步速与认知功能的关联.方法 2021年3-12月采用一般资料调查表、简易智能精神状态量表(mini-mental state examination,MMSE)、患者健康问卷抑郁量表和4.6 m步行试验对新乡市1 172名社区老年人进行问卷调查.依据步速五分位分组将老年人步速分为 Q1～Q5 组,[Q1 组(≤ 0.76 m/s),Q2 组(0.77～0.88 m/s),Q3 组(0.89～0.98 m/s),Q4 组(0.99～1.11 m/s),Q5组(≥1.12 m/s)].采用SPSS 25.0统计软件进行描述性统计,采用二元Logistic回归分析老年人步速和抑郁对认知功能的影响.结果 社区老年人的步速为(0.92±0.22)m/s,Q1～Q5组的 MMSE 得分分别为:(24.72±3.67)分、(26.63±2.90)分、(26.58±2.66)分、(27.01±2.45)分和(27.18±2.35)分,不同步速组社区老年人的认知功能差异有统计学意义(F=27.92,P＜0.05).二元Logistic回归结果显示,与Q1组比较,Q2～Q5组认知功能受损的OR值(95％CI)分别为0.475(0.253～0.893)、0.426(0.219～0.828)、0.421(0.212～0.826)、0.371(0.179～0.766),步速较快是认知功能的保护因素;高龄(OR=1.096,95％CI=1.053～1.140)、抑郁(OR=14.441,95％CI=12.670～19.829)是认知功能受损的危险因素.结论 社区老年人步速与认知功能存在关联,步速较快是认知功能的保护因素.
Abstract
Objective To explore the association of gait speed and cognitive function of the commu-nity-dwelling elderly.Methods From March to December 2021,a total of 1 172 Xinxiang community-dwell-ing elderly people were investigated by general information questionnaire,mini-mental state examination(MMSE),patient health questionnaire depression scale and 4.6 m gait test.The elderly were divided into five groups based on the quintile grouping of gait speed values,with Q1 group(≤0.76 m/s),Q2 group(0.77-0.88 m/s),Q3 group(0.89-0.98 m/s),Q4 group(0.99-1.11 m/s)and Q5 group(≥1.12 m/s).SPSS 25.0 statistical software was used for descriptive statistics,and binary Logistic regression was used to analyze the influence of gait speed and depression on cognitive impairment of the elderly.Re-sults The gait speed of community-dwelling elderly people was(0.92±0.22)m/s.The scores of MMSE in Q1-Q5 groups were(24.72±3.67),(26.63±2.90),(26.58±2.66),(27.01±2.45)and(27.18±2.35),respectively,and the cognitive function was significantly different among the five gait speed groups(F=27.92,P＜0.05).The results of binary Logistics regression showed that compared with Q1 group,the OR value(95％CI)of cognitive impairment in Q2-Q5 group were 0.475(0.253-0.893),0.426(0.219-0.828),0.421(0.212-0.826)and 0.371(0.179-0.766),respectively,which indicated that fast walking speed was a protective factor for cognitive function.Old age(OR=1.096,95％CI=1.053-1.140)and de-pression(OR=14.441,95％CI=12.670-19.829)were risk factors of cognitive impairment.Conclusion The gait speed is associated with cognitive function among community-dwelling elderly people,and faster gait speed is a protective factor for cognitive function.
基金项目
河南省高等学校重点科研项目资助计划项目(21A310013)
河南省医学科技攻关计划项目(LHGJ20220240)
新乡市慢性病基础研究与智能照护重点实验室项目()
Xinxiang Key Laboratory of Basic Research and Intelligent Care for Chronic Diseases()
NETL
NSTL
万方数据