摘要
目的 分析新生儿窒息危险因素及其与孕妇分娩方式、母儿围产结局的关系.方法 选取2019年1月—2023年1月南阳市中心医院收治的120 例新生儿窒息患儿作为观察组,120 名健康新生儿作为对照组;回顾性分析所有入组新生儿的临床资料并分析新生儿窒息危险因素.结果 观察组患儿呼吸系统疾病、脐带因素、胎盘因素、剖宫产、产妇高龄、宫内感染、母体贫血、先天疾病及早产儿发生率明显高于对照组,且差异有统计学意义(P＜0.05);观察组体质量＜2 kg患者比例显著高于对照组(P＜0.05);观察组TNF-α、IL-6及内脂素水平显著高于对照组(P＜0.05);呼吸系统疾病、脐带因素、胎盘因素、剖宫产、产妇高龄、宫内感染、母体贫血、早产儿、体质量＜2 kg、TNF-α、IL-6及内脂素是影响新生儿窒息发生的危险因素(P＜0.05).结论 母体因素、胎盘因素、脐带因素、胎儿因素均是影响新生儿窒息的危险因素,且孕妇分娩方式、母儿围产结局、TNF-α、IL-6及内脂素也是影响新生儿窒息发生的危险因素.
Abstract
Objective To analyze the risk factors of neonatal asphyxia and its relationship with the mode of delivery and perinatal outcomes of pregnant women.Methods 120 cases of neonatal asphyxia in Nanyang Central Hospital from January 2019 to January 2023 were selected as the observation group and 120 healthy neonates as the control group.The clinical data of all the neonates were retrospectively analyzed and the risk factors of neonatal asphyxia were analyzed.Results The incidence of respiratory diseases,umbilical cord factors,placenta factors,cesarean section,maternal age,intrauterine infection,maternal anemia,congenital diseases and premature infants in the observation group were significantly higher than those in the control group(P＜0.05).The proportion of patients with body mass＜2 kg in the observation group was significantly higher than that in the control group(P＜0.05).Respiratory diseases,umbilical cord factors,placenta factors,cesarean section were significantly higher than those in the control group(P＜0.05).The levels of TNF-α,IL-6 and endolipids in the observation group were significantly higher than those in the control group(P＜0.05).Respiratory diseases,umbilical cord factors,placental factors,cesarean section,advanced maternal age,intrauterine infection,maternal anemia,premature infants,body weight＜2 kg,TNF-α,IL-6 and endolipids were the risk factors for neonatal asphyxia(P＜0.05).Conclusion Maternal factors,placental factor,umbilical cord factor,and fetal factor are all risk factors for neonatal asphyxia,and maternal mode of delivery,maternal and infant perinatal outcomes,TNF-α,IL-6 and endolipids are also risk factors for neonatal asphyxia.
NETL
NSTL
万方数据