摘要
目的 探讨急性心肌梗死(AMI)患者的血清N-末端脑钠肽前体(NT-proBNP)水平与心肌钆剂延迟强化(LGE)、梗死节段数、心功能与NT-proBNP关系.方法 收集2018年4月—2024年4月AMI行经皮冠状动脉介入术(PCI)患者33 例,其中男31 例,女2 例,年龄44～76 岁,平均(54.3±10.6)岁.术后行心脏磁共振检查,分析有无LGE、梗死节段数、心功能与NT-proBNP关系.结果 30 例(90.9%)AMI患者PCI支架术后心肌LGE阳性,NT-proBNP高水平组左心室梗死面积较NT-proBNP低水平组大;NT-proBNP高水平组左心室射血分数(LVEF)较NT-proBNP低水平组差;高水平组左心室舒张末期容积指数(LVEDVI)较NT-proBNP低水平组差异无统计学意义;NT-proBNP高水平组左心室收缩末期容积指数(LVESVI)较NT-proBNP低水平组大.结论 AMI患者的NT-proBNP水平可间接评估左心室梗死面积、LVEF、LVESVI,提示临床完善心脏磁共振检查明确梗死区域及损害程度方便进行治疗.
Abstract
Objective To explore the relationship between serum N-terminal pro-brain natriuretic peptide(NT-proBNP)levels and late gadolinium delayed enhancement(LGE),number of infarcted segments,cardiac function,and NT-proBNP in patients with acute myocardial infarction(AMI).Methods 33 patients with AMI who underwent percutaneous coronary intervention(PCI)from April 2018 to April 2024 were collected,including 31 males and 2 females,aged 44-76 years,with an average age of(54.3±10.6)years.Cardiac magnetic resonance imaging was performed to analyze the relationship between LGE,number of infarcted segments,cardiac function,and NT-proBNP.Results 30(90.9%)of AMI patients showed positive myocardial LGE after PCI,and left ventricular infarct area was larger in the NT-proBNP high level group than in the NT-proBNP low level group.NT-proBNP high level group had lower left ventricular ejection fraction(LVEF)compared to NT-proBNP low level group.The high level group of left ventricular end diastolic volume index(LVEDVI)showed no significant difference compared to the low level group of NT-proBNP.Left ventricular end systolic volume index(LVESVI)was higher in the NT-proBNP high level group than in the NT-proBNP low level group.Conclusion NT-proBNP level in patients with AMI can indirectly evaluate the left ventricular infarct area,LVEF,and LVESVI,indicating the clinical to check by cardiac magnetic resonance imaging can clarify the infarct area and degree of damage for treatment.
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