Application Value of Decompressive Craniectomy Combined with Pterygoid Approach via Lateral Fissure Microscopy in Patients with Hypertensive Intracerebral Hemorrhage in Basal Ganglia
Application Value of Decompressive Craniectomy Combined with Pterygoid Approach via Lateral Fissure Microscopy in Patients with Hypertensive Intracerebral Hemorrhage in Basal Ganglia
Objective To explore the curative effect of Pterygoid approach via lateral fissure microscopy combined with decompressive craniectomy on patients with basal ganglion hypertensive intracerebral hemorrhage(HICH)and the influence of related serum protein indexes.Methods 97 patients with basal ganglion HICH in Henan Provincial Third Hospital from July 2022 to November 2023 were selected as study subjects,and were divided into the conventional group and the intervention group according to different surgical methods.48 patients in the conventional group were treated with small bone window minimally invasive surgery,while 49 patients in the intervention group were treated with Pterygoid approach via lateral fissure microscopy combined with decompressive craniectomy.The effects,neurological function indexes,related serum protein levels and surgical complications were compared between the two groups.Results Hematoma clearance rate,operation time and operation bleeding volume in intervention group were higher than those in conventional group 1 month after operation(P＜0.05).The levels of nerve growth factor(NGF),neuron-specific enolase(NSE)and Glasgow coma scale(GCS)score in the two groups at 7 days after operation were higher than those before operation,and those in the intervention group were higher than those in the conventional group.The intracranial pressure level at 7 days after operation was lower than that before operation,and the intervention group was lower than that of the conventional group(P＜0.05).The levels of heart fatty acid-binding protein(H-FABP)and S-100β in both groups at 7 days after operation were lower than those before operation,and those in the intervention group were higher than those in the conventional group(P＜0.05).The incidence of postoperative complications in the intervention group was 2.04%(1/49)lower than that in the conventional group[6.25%(3/48)],and the difference was not statistically significant(P＞0.05).Conclusion Pterional approach via lateral fissure microscopy combined with decompressive craniectomy can improve the serum protein level of patients with basal ganglia HICH by reducing the compression of hematoma on peripheral nerve,improve the surgical index,regulate nerve function,reduce the occurrence of surgical complications,and improve clinical efficacy.
关键词
翼点入路经侧裂显微术/去骨瓣减压术/高血压脑出血/血清蛋白水平
Key words
Pterional approach via lateral fissure microscopy/decompressive craniectomy/hypertensive intracerebral hemorrhage/serum protein level
维普
万方数据