Objective To evaluate the efficacy of three-port laparoscopic surgery versus Rutkow repair for inguinal hernia,and assess their impact on serum α1-antitrypsin(α1-AT)and soluble triggering receptor expressed on myeloid cells-1(sTREM-1)levels.Methods 66 patients undergoing inguinal hernia surgery between January 2022 and December 2023 were randomly assigned to either the laparoscopic group(n=33)or the Rutkow group(n=33).The laparoscopic group underwent three-port totally extraperitoneal(TEP)repair,while the Rutkow group received tension-free hernioplasty.Operative time,hospital stay,postoperative complications,recurrence rates,pain scores(VAS),quality of life scores(SF-36),and serum α1-AT and sTREM-1 levels were compared between groups.Results The laparoscopic group exhibited longer operative times but shorter hospital stays compared to the Rutkow group(P＜0.05).Postoperative complications and recurrence rates were significantly lower in the laparoscopic group(P＜0.05).VAS and SF-36 scores at 3,7,and 14 days post-surgery were more favorable in the laparoscopic group(P＜0.05).Serum α1-AT and sTREM-1 levels were notably reduced in the laparoscopic group at 3,7,and 14 days post-surgery(P＜0.05).Conclusion Three-port laparoscopic surgery for inguinal hernia demonstrates advantages over Rutkow repair,including reduced hospital stays,lower complication and recurrence rates,improved postoperative pain management and quality of life,and more effective reduction of serum α1-AT and sTREM-1 levels,indicating a milder inflammatory response and immune stress.
关键词
腹股沟疝/三孔法腹腔镜/Rutkow术/α1-抗胰蛋白酶/可溶性髓系细胞触发受体-1
Key words
inguinal hernia/three-port laparoscopy/Rutkow repair/α1-antitrypsin/soluble triggering receptor expressed on myeloid cells-1
维普
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