Immune thrombocytopenic purpura(ITP)is an autoimmune disorder characterized by reduced platelet counts and an increased risk of hemorrhagic conditions.The pathophysiology of ITP is complex,and while corticosteroids and immunosuppressants are effective in managing the symptoms,these treatments can lead to adverse reactions and are not curative.Mesenchymal stem cells(MSCs),known for their unique immunomodulatory capabilities,have been employed in the treatment of various autoimmune diseases.Recent studies have underscored the significant role of MSCs in the therapeutic landscape of ITP.This review summarizes the latest research on the application of MSCs in treating ITP,discussing their therapeutic potential and future research directions.