吡仑帕奈相关不良反应
Adverse reactions related to perampanel
雒晨宇 1毕锦玉 1杜涛涛 1孙美珍2
作者信息
- 1. 山西医科大学,山西太原 030000
- 2. 山西医科大学第一医院神经内科,山西太原 030000
- 折叠
摘要
自2012年获得美国食品和药物管理局批准上市以来,吡仑帕奈的抗癫痫疗效和安全性已在50多个国家得到证实,但其所致的不良反应不容忽视.吡仑帕奈常见不良反应有头晕、嗜睡、精神和行为反应、共济失调、体重增加和鼻咽炎;此外,还有自杀风险、皮疹、血小板减少和泌尿系统不良反应的报道.
Abstract
Since being approved by United States Food and Drug Administration in 2012,the antiepileptic efficacy and safety of pirenpamil have been confirmed in more than 50 countries,but its adverse reactions cannot be ignored.The common adverse reactions of perampanel include dizziness,drowsiness,mental and behavioral reactions,ataxia,weight gain,and nasopharyngitis.In addition,suicide risk,rash,thrombocytopenia,and adverse reactions of urinary system were also reported.
关键词
癫痫/抗癫痫药/吡仑帕奈/药物不良反应/受体,AMPAKey words
epilepsy/antiepileptic agents/perampanel/adverse drug reactions/receptors,AMPA引用本文复制引用
出版年
2023
NETL
NSTL
维普
万方数据